The main ingredient in Kamagra jelly is sildenafil citrate, a chemical that belongs to the PDE5 inhibitor class of ED medications. This group of drugs, which also includes Viagra, Levitra (vardenafil), Cialis (tadalafil), and Stendra (avanafil), works by inhibiting an enzyme in your body called phosphodiesterase 5, thereby allowing blood vessels to relax. This allows more blood to flow into your penis, leading to erections that are firm enough for sexual arousal.Because it’s not FDA-approved, however, you can’t be sure how much sildenafil citrate is actually in each packet of Kamagra jelly. It may be less than the recommended dosage or it may be too high, potentially causing serious side effects. Furthermore, unlicensed ED medications like Kamagra can interact with other medicines that you’re taking for high blood pressure or heart disease—including nitrates and alpha-blockers. This puts you at risk of dangerous comorbidities that can be deadly.